Novadip Secures €10.4M for Pivotal Phase 3 Bone Repair Cell Therapy Trial
The ongoing US and EU study is testing NVD003, an autologous cell-based therapy, in patients with a rare, difficult-to-treat pediatric bone condition.
Tissue Engineering
Made Scientific Acquires Resilience’s 85K-Square-Foot Cell Therapy Facility
The operational site and its team have completed 145 batches under good manufacturing practice standards, enabling immediate client onboarding.
Humacyte’s Vascular Tissue Graft Nabs FDA Authorization for 36-Month Shelf Life
Additional stability data showed the bioengineered vessel maintains quality specifications for three years under approved refrigeration, giving hospitals greater inventory flexibility for urgent vascular repairs.
Made Scientific Selected to Manufacture Columbia University’s NOVAKnee, a 3D Printed Knee Replacement Made of Stem Cells and Scaffolds
The Living Knee project is hoping to replace traditional knee replacements, expected to begin Phase 1 trials around 2028.
BioStem Technologies Receives 5 Patents for Placental Allografts
The 4 US and 1 European patents cover the design and manufacturing of the company's placental therapies. The company is targeting various applications across orthopedics, urology, and wound care.
Kangstem Publishes Promising Phase 1 Results for Cord-Blood Derived Stem Cell Therapy in Knee Osteoarthritis, Post-MRI Data Suggest Potential Cartilage Regeneration
The Korean biotech company published the multicenter Phase 1 results in Nature, with 24-week follow-up MRI data that look promising as they continue development.
Royal Biologics and Jellagen Bringing Jellyfish-Derived Collagen Type Zero to the US Regenerative Medicine Market
The companies are working to bring jellyfish-derived Collagen Type Zero to North America, aiming to advance wound care and regenerative medicine with a sustainable alternative to mammalian collagen.
Colorado Boulder’s Injection Shows Promise for Reversing Osteoarthritis, Advancing ARPA-H Project
Researchers in Colorado are advancing injectable and biomaterial-based therapies that, in animal studies, restored damaged cartilage and bone by triggering the body’s own repair processes, potentially offering a minimally invasive alternative to pain management or joint replacement.
Orthocell Secures US Department of Defense Approval for Remplir Collagen Nerve Wrap
Orthocell has gained approval for its Remplir nerve repair device across U.S. Department of Defence and Veterans Affairs hospital networks, expanding access to more than 220 military and veteran care facilities as it uses its distributor network to drive adoption in trauma-focused surgical settings.
Scripps Health Receives $12.7 Million Grant for Stem Cell Knee Research
The San Diego non-profit has received a $12.7 million grant to advance scaffold-free tissue engineering research aimed at repairing knee cartilage and bone damage.
FibroBiologics Files Patent for New Fibroblast-Derived Platform for Orthopedic Indications
The company says its platform may fundamentally change how cartilage loss and degenerative joint disease is treated globally.
Cellino and Polyphron Teaming Up to Scale Personalized Tissue Manufacturing Derived from iPSCs
Polyphron will use Cellino's induced pluripotent stem cells in its "autonomous tissue foundry" to reproducibly manufacture cell and tissue therapies at scale.
Japan Approves JTEC’s Cartilage Cell Therapy for Knee Osteoarthritis, Now Covered by Insurance
The company's autologous cartilage repair product will now be reimbursed under national health insurance, WOMAC scores improved better than hyaluronic acid injections.
Xtant Medical Launches New Synthetic Bone Graft, nanOss Strata, for Enhanced Healing
The new graft material is designed for improved integration with patients' tissues, and it's available through distributors now.
Celularity to License its Amniotic Biologics to Opthalmic Startup DefEYE
Celularity and DefEYE’s agreement aims to accelerate the development and commercialization of advanced regenerative biologic solutions for ophthalmic care.
Mayo Clinic Develops Stem Cell Patch to Potentially Repair Heart Damage Without Surgery
Researchers are testing a minimally invasive stem cell patch that could reduce the need for transplants.
Keensight Capital Takes Majority Ownership in Orthobiologics Firm Isto Biologics
Keensight Capital’s investment aims to accelerate Isto Biologics’ growth and international expansion in the orthobiologics sector.
TheWell Bioscience Introduces VitroGel® NEURON, a Synthetic Hydrogel Enhancing Neuronal Cell Culture
Designed for 2D and 3D cultures, this platform aims to offer greater consistency and scalability in neuronal research.
Tel Aviv University to Implant Lab-Grown Spinal Cord in Human Trial, Derived from Stem Cells
Researchers have seen good success in animal studies, and are advancing to the first clinical trials in humans. What a time to be alive.
Orthocell’s Collagen Nerve Wrap, Remplir, Now Available to Australian Urologists for Prostate Surgery Recovery
Australian urologists can now access Remplir to support nerve protection and recovery during robotic prostate cancer surgeries.
Kerecis Expands Fish-skin for Wound Care Lineup
The latest additions aim to support clinicians treating smaller wounds, enhancing flexibility and workflow in surgical wound care.
Orthocell Reports 81% Success Rate in Nerve Repair Study With Remplir
Interim study results highlight Remplir’s consistent safety and effectiveness in nerve repair, supporting further clinical and regulatory efforts.
Kyoto University Team Creates Jawbone Tissue from Human Stem Cells (iPSCs)
Researchers generated 3D jawbone tissue from induced pluripotent stem cells
Silk Based Nerve Repair Technology begins Trials
The first use of silk-based SilkAxons™ aims to address large peripheral nerve injuries where current treatments fall short.
NASA’s New Mission will Study Stem Cell Expansion in Space
The Crew-11 mission launched on Friday, where they will support studies in stem cell growth, organ tissue, bacteriophage therapy, and advanced computing.