Researchers administered the vesicles intranasally over time to female mice genetically engineered to model Alzheimer’s and separately tested them in neurons grown from patients’ induced pluripotent stem cells.
The published Phase I/IIa study found that MSC therapy reduced markers of brain inflammation and improved depression, fatigue, pain, and imaging biomarkers in adults with chronic traumatic brain injury, supporting ongoing larger controlled trials.
Developed in hand with the DoD, the company is hoping to lay the groundwork for cell therapy in concussive injuries for soldiers, athletes, and the broader population.
Their Chinese Phase 1 reportedly showed motor improvement in 90% of patients. With that data in hand, the FDA is allowing them to move forward out West.
Researchers report that intranasal Muse cells improved motor function and reduced neurodegeneration in a Parkinson’s mouse model.
For decades, treating diseases of the central nervous system (CNS) with stem cells has been hampered by one persistent biological obstacle: the blood–brain barrier (BBB). While the BBB protects the brain from harmful substances, it also blocks most drugs and…
Researchers may now have a new tool to unlock insights into blood-brain barrier regulation and neurological disease mechanisms.
NurExone Biologic's exosome product moves one step closer to clinical trials with their latest data, published in Cyotherapy.
Traumatic brain injury (TBI) occurs when trauma disrupts normal brain functions, potentially causing severe physical, cognitive, and emotional impairments. Researchers are exploring stem cells as a possible treatment because these cells might help prevent further brain deterioration and encourage the…
Link to study, found in the journal named Reports, dated 2024. The problem? Neuropathy of the lower leg caused by tarsal tunnel syndrome Symptoms include Sharp shooting pain Pins/needles Electric shock/burning sensations Credit Healthline.com The treatment studied? Wharton’s Jelly injected…