The retrospective analysis compared 76 phase 1b participants with 360 historical registry patients selected using similar age, diagnosis, conditioning and donor-match criteria.
The Canadian study will test whether the retrievable implant safely supports donor islets while preventing immune cells from reaching them.
A planned preclinical study will compare MicronJet’s suprachoroidal administration with existing methods, testing whether it can place exosome formulations consistently near the retina and optic nerve.
The C$1 million grant will support development of an oral medicine designed to restore blood-forming stem cells and rebuild the immune system.
Instead of waiting for a complete submission, the program will let selected sponsor–research institution pairs send IND sections for rolling pre-IND review to spot problems earlier.
The blood-derived, off-the-shelf cells are administered directly to the lungs through a standard nebulizer, with first U.S. patient dosing targeted for late 2026.
Researchers used whole-genome sequencing and a machine-learning RNA assay to assess dopamine neuron precursors made from patients’ skin cells for identity and consistency.
The initial program will use qualified perinatal starting materials and the licensed Dezawa Method, with product-specific testing and release criteria.
The ongoing US and EU study is testing NVD003, an autologous cell-based therapy, in patients with a rare, difficult-to-treat pediatric bone condition.
The operational site and its team have completed 145 batches under good manufacturing practice standards, enabling immediate client onboarding.