Encellin and Breakthrough T1D Planning Phase 1 of Immune-Protected Cell Therapy for Type 1 Diabetes
The Canadian study will test whether the retrievable implant safely supports donor islets while preventing immune cells from reaching them.
Endocrinology / Metabolism News
Trial – Human Umbilical Cord Mesenchymal Stem Cell Injection Evaluated for Diabetic Nephropathy
Tongji Hospital is recruiting 15 participants for a single-center, dose-escalation Phase 1 study primarily assessing adverse events through 48 weeks after treatment.
Syntax Bio and Mayo Clinic Partnering on Cell Therapy for Type 1 Diabetes
Syntax is bringing its Cellgorithm cell-therapy discovery platform to the table, while Mayo Clinic will provide expertise in pancreatic biology and functional testing for preclinical diabetes.
Sana Biotechnology and Mayo Clinic Partner Up on Type 1 Diabetes Stem Cell-Derived Therapy, Phase 1 Potentially This Year
The partnership hopes to speed up the scalable development of SC451 for type 1 diabetes by standardizing treatment protocols, improving clinical delivery and post-care, and preparing the therapy for broader use across care sites.
NextCell Reports Positive 7-Year Data for its Stem Cell Candidate, ProTrans, for Type 1 Diabetes
Long-term follow-up suggests ProTrans may help preserve insulin production, with results varying by dose.
Aspect Biosystems Acquires Novo Nordisk’s Diabetes Stem Cell Therapy Tech
After stepping back from stem cell therapies last year, Novo is passing the torch on diabetes cell therapies to Aspect Biosystems, who will continue to commercialize the tech.
Cytora Therapeutics Teams Up with Made Scientific and Zeo ScientifiX to Launch Stem Cell Therapy for Diabetic Foot Ulcers in the US
The partnership will focus on bringing oral mucosal stem cell therapy for diabetic foot ulcers to Florida, with FDA trials planned.
FDA’s New Regulatory Pathway May Forego RCTs for Ultra-Rare Conditions
Dr. Marty Makary and Dr. Vinay Prasad publish new article in New England Journal of Medicine, proposing a new pathway. Here are the details.
Celularity Reports Phase 2 Trial Results on Placenta-Derived Cell Therapy for Diabetic Foot Ulcers with Peripheral Artery Disease
The Phase 2 study showed good results for placenta-derived cell therapy for diabetic foot ulcers complicated by PAD.
CIRM Approves $73 Million for Early-Stage Regenerative Medicine Research in California
The new grants will support diverse early-stage research projects, aiming to advance regenerative medicine tools and future therapies.
Sana Biotechnology Reports Positive Results in Type 1 Diabetes Study Using Transplantation Without Immunosuppression
Sana Biotechnology reported six-month clinical data demonstrating successful survival and function of transplanted islet cells without immunosuppressive medication.
NextCell Pharma Completes Patient Dosing in Pediatric Diabetes Stem Cell Study
The company has concluded dosing in its largest pediatric diabetes trial, evaluating ProTrans therapy's safety and insulin-preserving potential
Vertex Reports Promising Results from Stem Cell Trial for Type 1 Diabetes
Vertex recently presented encouraging Phase 1/2 results for zimislecel, a stem cell-derived therapy showing sustained insulin production in type 1 diabetes patients.
Pharmaceutical giant GSK sees stem cells as useful for drug discovery and therapeutics
In a recent policy position statement, GlaxoSmithKline (GSK) mentioned that stem cell technology has its use cases in drug discovery, albeit it needs to be done in an ethical, safe way. Here's what they said: Stem cells are an integral…